Rafael van der Vaart's speculative long shot just before halftime sent Tottenham Hotspur into the FA Cup fifth round with a fortunate 1-0 win at Watford on Friday.
Chelsea banished any fears of a repeat of last season's shock FA Cup fourth-round exit to Bradford City when they crushed Championship (second-tier) side Milton Keynes Dons 5-1 away to reach the fifth round on Sunday.
Real Madrid said their participation in the tournament was never in question.
Fellow Serie A sides Atalanta and Lazio also won while Portugal's Vitoria Guimaraes began their match against Salzburg with not a single European player in the team.
The race for Premier League places in next season's Europa League warmed up on Sunday when Aston Villa and Everton fought out a thrilling 3-3 draw and Fulham came from behind to win 3-1 at Manchester City.
Phil Foden struck twice as Manchester City stepped up their bid for a fourth Premier League crown in a row with a ruthless 4-0 victory at Brighton & Hove Albion on Thursday.
A stoppage-time goal from Martin de Roon earned Middlesbrough an unlikely 1-1 draw at Premier League leaders Manchester City on Saturday.
A summary of Sunday's action in the Premier League.
Manchester City's fingertip hold on their Premier League title was further loosened when a 2-0 loss at Everton followed by runaway leaders Manchester United's 1-0 win over Reading left them praying for a football miracle.
Holders Manchester City beat Chelsea 1-0 with a late Bernardo Silva goal on Saturday to reach the FA Cup final after an absorbing end-to-end Wembley semi-final left the exhausted winners still chasing a domestic double.
Manchester City went top of the Premier League, at least until Manchester United play at Stoke City later on Saturday, when they beat Everton 2-0 at the Etihad Stadium with goals from second-half substitutes Mario Balotelli and James Milner.
Cristiano Ronaldo came off the bench to earn Manchester United a hard-fought 2-1 victory at Everton in the Premier League on Sunday, taking his career goal tally to 700 in the process.
Manchester City's Argentina striker Carlos Tevez scored a hat-trick two days after he was arrested as they cruised past Barnsley 5-0 to join history makers Wigan Athletic in the FA Cup semi-finals on Saturday.
Everton can take a huge step towards an unlikely top-four finish and Champions League soccer next season if they can maintain their recent run of great form by winning at Arsenal for the first time in 17 years on Tuesday.
Frank Lampard underlined his value to Chelsea with a well-taken double that secured a 2-1 comeback win at Everton on Sunday to move the Londoners back up to third place in the Premier League.
Everton ended third-tier Oldham Athletic's giantkilling FA Cup run with a 3-1 victory in their fifth round replay on Tuesday to tee up an all Premier League quarter-final against Wigan Athletic.
On-loan Bolton Wanderers striker Daniel Sturridge scored his third goal in three games to wrap up a 2-0 victory over Everton in the Premier League on Sunday.
Atalanta beat Bayer Leverkusen 3-0 in the Europa League final
Striker Wayne Rooney was included in Manchester United's squad to play at Everton on Saturday after more than a month out with a broken bone in his foot.
While England boast a formidable attacking threat, there are concerns about their defence which is perhaps why Southgate is prepared to look at new candidates before he has to make his final call for the tournament.
Everton get the chance to put a large dent in Manchester United's title hopes when they face the Premier League's injury-hit leaders at Goodison Park on Saturday.
Tottenham Hotspur scored three late goals to beat Bolton Wanderers on Tuesday and set up an FA Cup semi-final against Chelsea, after replaying the game that was abandoned when midfielder Fabrice Muamba suffered a cardiac arrest on the pitch.
A summary of sports events and sports persons, who made news on Thursday.
Images from the English Premier League matches played on Saturday
Manchester United wasted a glorious chance to catch Chelsea at the top of the Premier League when they lost 1-0 at home to Aston Villa on Saturday. Earlier leaders Chelsea were held 3-3 at home by Everton despite two goals from Didier Drogba.
Ruthless Arsenal threw down the gauntlet in the Premier League title race with a 5-0 thrashing of London rivals Chelsea to roar three points clear at the top of the table on Tuesday.
IMAGES from the English Premier League matches played on Saturday.
IMAGES from the soccer matches played across leagues on Friday
Manchester City took another decisive step toward an unprecedented fourth successive Premier League title with a 4-0 demolition of Fulham.
The England striker's transfer value soared to 50 million pounds following his Euro 2004 performances.
Steven Gerrard scored two penalties as Liverpool went back to the top of the Premier League with a 2-1 win at West Ham United to complete a Merseyside win-double over London clubs on Sunday.
A summary of Saturday's matches in the English Premier League.
Everton scored twice in stoppage time to snatch an unlikely 3-3 home Premier League draw with Manchester United on Saturday in a game that Wayne Rooney missed to spare him from potential crowd abuse.
Chelsea beat Newcastle United 2-0 for a 10th successive Premier League home win at their Stamford Bridge stronghold on Saturday to reassert themselves as Premier League leaders while champions Manchester City drew at Everton.
Arsenal's victory ended a run of three successive defeats in all competitions and put them level on 43 points with Aston Villa and champions Manchester City. Arsenal's goal difference is superior to Villa's but worse than City's.
IMAGES from the Premier League match played between Liverpool and Luton at Anfield on Wednesday
Tottenham Hotspur continued their Premier League title push with a 2-0 win over Everton on Wednesday to put them level on points with second-placed champions Manchester United and three behind leaders Manchester City.
IMAGES from the English Premier League matches played on Tuesday.
Gerrard's side turned their fortunes around at the expense of the visitors under Lampard
IMAGES from Premier League matches played on Saturday.